Finally, in 1885, he had some success with On the Stage – and Off (1885), a comic memoir of his experiences with the acting troupe, followed by Idle Thoughts of an Idle Fellow (1886), a collection of humorous essays which had previously appeared in the newly founded magazine, Home Chimes, the same magazine that would later serialise Three Men in a Boat. Over the next few years, he was a school teacher, a packer, and a solicitor's clerk. He tried to become a journalist, writing essays, satires, and short stories, but most of these were rejected. After three years on the road with no evident success, the 21-year-old Jerome decided that he had enough of stage life and sought other occupations. He joined a repertory troupe that produced plays on a shoestring budget, often drawing on the actors' own meagre resources – Jerome was penniless at the time – to purchase costumes and props. Jerome published an autobiography My Life and Times in 1927.Jerome was inspired by his older sister Blandina's love for the theatre, and he decided to try his hand at acting in 1877, under the stage name Harold Crichton. Jerome (18591927), British author Jerome Kagan (19292021), American psychologist Jerome Karle (19182013), American chemist Jerome Kern (18851945), American composer Jerome Kohl (19462020), American musicologist Jerome 'Jerry' Kuehl, (1931-2018), historian and tv producer Jerome H. (After being sued for libel, Jerome was forced to sell his interests in both magazines to cover costs of nine thousand pounds.) Other work included Three Men on the Bummel which was published in 1900, Paul Kelver (1902) and a play The Passing of the Third Floor Back (1908) and All Roads Lead to Calvary (1919). He was also the editor of The Idler, a monthly publication, and To-Day, a weekly. Jerome continued writing and left eight novels, collections of sketches and short stories, autobiographical work, plays and journal articles.

In was only in 1968 that Weeds (1892) became known as one of his works. His second novel Weeds (1892) was published anonymously, and because of the nature of the content, a story of sexual corruption, his publisher halted the sale of the book. He also ran into prejudice because he was a member of the lower-middle class.

Despite the success of his first book, Jerome experienced problems because reviewers refused to take his subsequent work seriously. This book, a comic masterpiece, proved to be incredibly popular and he became a literary sensation. Jerome began writing Three Men in a Boat after his marriage in 1888, and the book was published in 1889.

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